Hearing Loss Treatment Research, by Akouos
Can anyone tell me what kind of research Eli Lilly’s recently acquired Akouos is doing? https://investor.lilly.com/news-releases/news-release-details/lilly-acquire-akouos-discover-and-develop-treatments-hearing
Gene therapy for genetic hearing loss I think. Specifically “gene therapy intended for the treatment of hearing loss due to mutations in the OTOF gene”
“The first participant to receive AK-OTOF in the study, an 11-year-old at the time of AK-OTOF administration with profound hearing loss from birth, experienced restored hearing within 30 days of AK-OTOF administration. In this individual, hearing was restored across all tested frequencies, achieving thresholds of 65 to 20 dB HL, and within the normal hearing range at some frequencies at the Day 30 visit. Both the surgical administration procedure and the investigational therapy were well tolerated, and no serious adverse events were reported.”