Yes, all the one’s that have been reported on the HAF had gone to clinical trials. I’ve been on the HAF for 8 years and in that time I think there has been at least 6 or 7 reports of breakthroughs in restoring lost hearing. So far none have made it through their trials.
Frequency Therapeutics announces breakthrough small-molecule approach to regenerate inner ear sensory hair cells
Ok, I’ve kind of adopted this as my thing. Here’s their latest press release quoted verbatim. More importantly there’s a video from their Chief Scientific Officer explaining the concepts. Probably the most succinct explanation I’ve seen. Whether you believe it or not, it’s definitely interesting.