As long as you don’t mute the mics, you should be ok.
Since I switched out the formula from DSL to VAC+ I’m finding car audio (music) quite pleasing without much further tinkering of the stock VAC settings.
Talk radio isn’t bad either, catching most words and getting the gist of the conversation.
I was previously using the stock music settings but it allowed too much road and external noise.
Yes this is what most music programs are doing, turning off all the unnecessary processing.